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Markers | Indications | Diagnosis acute MI | Prognostic value | Risk unstable angina | Therapy decision | Reperfusion monitoring

The Cardiovascular Challenge

 

 

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Cardiovascular diseases contribute to about half of all deaths in industrialized countries. Epidemiological studies demonstrated a similar trend in developing countries.

 

 WHO: Epidemiological Data

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About 14 million people die each year worldwide because of cardiovascular diseases.

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About 20% of all deaths worldwide are caused by cardio vascular diseases.

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About 50% of all deaths in industrialized countries are caused by cardiovascular diseases, the most common disease categories are ischemic heart disease, cerebrovas cular disease and hypertension

 

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The most critical challenge to treating physicians is the differential diagnosis of acute coronary syndromes, including:

  1. Myocardial infarction (Ml),

  2. Unstable angina pectoris,

  3. Stable angina pectoris and

  4. Minor myocardial damage.

 

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Accurate diagnosis reduces the costs of unnecessary hospital admissions of patients with chest pain.

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Approximately 35 to 70% of the annual admissions to coronary care units in industrialized countries are considered to be unnecessary admissions

 

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This clinical guide on the use of cardiac markers provides an overview of most recent guidelines as issued by the following international associations:

  1. WHO (World Health Organization,

  2. ACC (American College of Cardiology),

  3. AHA (American Heart Association)

  4. NACB (U.S. National Academy of Clinical Biochemistry) and

  5. ESC (European Society of Cardiology).

 

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