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[Up] [Glucose Tolerance Test] [Gestational Diabetes]

 

 

Glucose tolerance test (GTT)

 

 

Significance

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Done to confirm or rule out diabetes.

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Can also indicate those at risk of developing diabetes in future

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Procedure

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Person to be tested must be on their usual diet ,exercise and routine schedule for at least 3 days prior to the test.

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Test be carried out in the morning after fasting for 8 hours; blood is collected in the fasting state.

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75 grams of anhydrous glucose ( for children the dose is 1.75 grams of glucose per kg of body weight up to maximum of 75 grams.) is given orally; this may be dissolved in water to avoid nausea; it may be flavored with a little lime to make it more palatable; the glucose solution should be ingested within 4-5 minutes. If glucose monohydrate ( which is the form of glucose most commonly available in the market) is used,82.5 gms. must be administered.

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The person must rest throughout the test.

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Smoking must not be permitted during the test.

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A note be made of any factor which may interfere with the correct interpretation of the test (e.g. medications, in activity, infections etc.)

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Blood is collected 2 hours after glucose ingestion.

 

The results are interpreted according to WHO criteria.

  1. Impaired Glucose Tolerance Test ( IGT)

    Many patients in this category will go on to have diabetes.

  2. Many IGT patients show associated problems like hypertension, lipid disorders, high uric acid, obesity etc, which merit treatment.

  3. IGT is a risk factor for the development of macro vascular disease.

 

Impaired Fasting Glycemia (I.F.G)

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Recently introduced to delineate persons in whom only the fasting blood glucose has been done ,but who do not come in the normal or diabetic category.

 

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It has been proposed that the diagnosis of diabetes can be made from a fasting blood glucose level only and that it may not be necessary to do a complete GTT.

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However these patients with I.F.G. should be confirmed with a complete glucose tolerance test ,if feasible.

 

Normal result

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Values not falling within any of the above categories signifies a normal tolerance to glucose.

A negative test only shows that the patient is not diabetic at the time of testing; it does not mean that he will never develop diabetes; such persons must have an annual checkup.

 

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