Asthma over view
Jaundice Hepatitis A
CT MRI Xray
Discounts Lab tests
[Up] [Hypothyroidism classification] [Risk factors] [Clinical features] [End organ impact] [Associated illnesses] [Diagnosis] [Treatment] [Dose titration] [Drug interactions] [Monitoring & follow up] [Myxedema coma]
The initial dose of
thyroxin sodium administered depends on
The dosage needs to be titrated against TSH levels according to individual patient's needs.
The patient should be reevaluated and the serum TSH level should be measured in about 6 - 8 weeks.
The dose of
thyroxin should be increased if the serum TSH concentration is elevated and decreased if it is low.
Individualization and titration of proper dose is critical, aiming at normalization of serum TSH levels.
If proper dosage adjustment is not done then under treatment can lead to persistence and exacerbation of symptoms can lead to end organ damage, while over treatment can lead to following side effects
Side effects of over treatment with
Thyrotoxicosis due to thyroid hormone
Increased intracranial pressure
Accelerates bone loss in postmenopausal women
Increased heart rate
Increased left ventricular wall thickness and contractility