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 Factors influencing the requirements of thyroxin sodium treatment

 

 Increased requirement

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Pregnancy 

 

 Drugs leading to decreased absorption of thyroxine 

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Sucralfate 

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Aluminium hydroxide 

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Ferrous sulphate 

 

 Drugs leading to increased clearance of thyroxine 

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Rifampicin

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Carbamazepine

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Phenytoin

 

 Drugs that prevent conversion of T4 to T3 

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Glucocorticoids 

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Amiodarone

  • Depending on the above factors dose of thyroxin sodium may need adjustment.

 

 

 

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